My mothers laptop does this every so often (once every few days). Mouse can still move about the screen, but nothing can be clicked on.
CTRL+ALT+F commands work and I can login via terminal, startx to make a traditional gnome gui under root appear and use the pc as normal.
I can log out and back in to the user account but the display remains in this state.
The only solution so far is to restart the PC via terminal or another x session
Zorin OS 16 standard
lock screen is disabled
display set to turn off after 5 mins
AMD 2500U + vega 8 APU
I cannot recreate the issue manually locking or logging in/out, letting monitors power save, etc.