Yes, you can remove the Windows drive and install Zorin on the other drive. Then, reconnect the Windows drive, but boot into Zorin. In the Zorin OS; open a terminal and run
sudo update grub
before trying to boot Windows.
BUT- you do not NEED to remove the Windows drive to install and since I believe you said this is a Notebook PC, you may prefer to not disassemble the Notebook. In this case, with both drives connected, boot into your USB copy of Zorin and choose the installer.
You will need to choose the “Something Else” method. This will open a disk manager, within which you can choose sdb as your installation drive. You can ensure that the sdb you choose is the HDD and not the USB Stick by looking at its Size.
I cannot install Windows on a drive and then install Zorin on another in order to create and post helpful screenshots. I have also tried searching the web for a similar guide that has screenshots, but have come up empty handed.
Another option may be to catch one of us online and you post pictures of your screen as you go so we can confirm or verify the next step as you go through the steps to ensure everything goes smoothly.