In the bios I changed "Wake up Event by" to OS instead of Bios. Now the mouse and k/b do not wake the pc when I "power off".
I'm currently waiting 15 minutes for it to automatically suspend to see if the mouse/kb will still wake it from that state.
Edit: And now it won't wake from suspend with the mouse keyboard.
It does wake, quickly from the suspend state, when I push the physical power button.