Sorry, the stuff about GUI confused me
I think I'm following what you're saying now!
I ran the above commands in the CLI, uninstalled the Bible Study app and tried to reinstall it, but got the 0x80070643 error.

david@david-HP-Laptop-15s-fq1xxx:~$ sudo dpkg --add-architecture i386
[sudo] password for david:
david@david-HP-Laptop-15s-fq1xxx:~$ sudo apt install zorin-windows-app-support
Reading package lists... Done
Building dependency tree
Reading state information... Done
zorin-windows-app-support is already the newest version (1.1).
0 to upgrade, 0 to newly install, 0 to remove and 0 not to upgrade.
david@david-HP-Laptop-15s-fq1xxx:~$ sudo apt install winetricks
Reading package lists... Done
Building dependency tree
Reading state information... Done
winetricks is already the newest version (0.0+20180217-1).
0 to upgrade, 0 to newly install, 0 to remove and 0 not to upgrade.
david@david-HP-Laptop-15s-fq1xxx:~$ sudo winetricks --self-update
Executing cd /tmp/winetricks.Gz3c2IvP
Downloading https://raw.githubusercontent.com/Winetricks/winetricks/master/src/winetricks to /tmp/winetricks.Gz3c2IvP
--2021-03-19 14:30:11-- https://raw.githubusercontent.com/Winetricks/winetricks/master/src/winetricks
Resolving raw.githubusercontent.com (raw.githubusercontent.com)... 185.199.110.133, 185.199.111.133, 185.199.108.133, ...
Connecting to raw.githubusercontent.com (raw.githubusercontent.com)|185.199.110.133|:443... connected.
HTTP request sent, awaiting response... 200 OK
Length: 880974 (860K) [text/plain]
Saving to: 'winetricks’
winetricks 100%[===================>] 860.33K 316KB/s in 2.7s
2021-03-19 14:30:15 (316 KB/s) - 'winetricks’ saved [880974/880974]
Executing cd /home/david
Executing mv /tmp/winetricks.Gz3c2IvP/winetricks /usr/local/bin/winetricks.update
Executing rmdir /tmp/winetricks.Gz3c2IvP
Executing cp /usr/local/bin/winetricks /usr/local/bin/winetricks.bak
Executing chmod -x /usr/local/bin/winetricks.bak
Executing mv /usr/local/bin/winetricks.update /usr/local/bin/winetricks
Executing chmod +x /usr/local/bin/winetricks
Update finished! The current version is 20210206-next - sha256sum: 9f64e526c35d661c50db78f2ca1a8e7ec44f112e514cf3d9e71c40490276a8d0. Use 'winetricks --update-rollback' to return to the previous version.
david@david-HP-Laptop-15s-fq1xxx:~$ winetricks -q dotnet462
warning: Your version of wine 4.0.3 is no longer supported upstream. You should upgrade to 5.x
Executing mkdir -p /home/david
warning: You are using a 64-bit WINEPREFIX. Note that many verbs only install 32-bit versions of packages. If you encounter problems, please retest in a clean 32-bit WINEPREFIX before reporting a bug.
Using winetricks 20210206-next - sha256sum: 9f64e526c35d661c50db78f2ca1a8e7ec44f112e514cf3d9e71c40490276a8d0 with wine-4.0.3 and WINEARCH=win64
Executing w_do_call dotnet462
Executing mkdir -p /home/david
warning: You are using a 64-bit WINEPREFIX. Note that many verbs only install 32-bit versions of packages. If you encounter problems, please retest in a clean 32-bit WINEPREFIX before reporting a bug.
dotnet462 already installed, skipping
david@david-HP-Laptop-15s-fq1xxx:~$