One small issue I encounter with Zorin Layouts is that every time I switch layouts, the file manager settings I configured for single-click revert to double-click, and this has become quite frustrating for me. 
I am wondering if the double-click function ties in with Windows like themes only? Migrants from Windows might prefer this to single-click.
I can't recall anything regarding Windows, but I feel that Nautilus settings shouldn't affect the layout.