Yes, you can. Create a desktop entry for the appimage an then place it in ~/.local/share/appliations
Open a new file in text editor and paste the following into it:
[Desktop Entry]
Name=
Comment=
Exec=
Icon=
Terminal=false
Type=Application
Categories=
Name is name of the appimage. Comemnt is whatever description you want to have with it. Exec=/path/to/appimage/file
icon=/path/to/icon/that/you/want/to/use
Categories - choose a category for it to appear under in the menu.
Save when done.