HP Pavilion Laptop won't wake from sleep with Zorin OS 16

I would encourage you to roll your kernel back to a known working and AMD supported kernel.
We can try the 5.8 first and if that fails, the 5.4...

sudo apt install linux-headers-5.8.0-63-generic linux-modules-5.8.0-63-generic linux-modules-extra-5.8.0-63-generic linux-image-5.8.0-63-generic

Once installed, reboot, then from grub, tap the tab button to see Advanced options for Zorin. Move to the 5.8 kernel and boot into it.
Test the system and relay the results.

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