I know it's vague but it's because I really can't find the source of the problem.
Regularly everyday, mostly when playing game, the os does the sound of like something is plugged out, then back it.
It seems graphic since even the toolbar seems to change slightly (icons moving a bit) when it occurs.
Did anybody have a similar issue?
I precise I'm running a laptop with AMD graphics.
Thanks 
Is Secure Boot & Fast Boot disabled in the BIOS? I would start there.
You say you have an AMD GPU, that means the driver should already be in the kernel, and as such, shouldn't be giving you issues.
I suspect that your computer isn't brand spanking new, as of this month, which mean's, you shouldn't be facing kernel too old issues.
CTRL ALT T to enter terminal. Run the following commands please.
sudo apt install neofetch
Now just run neofetch
Please take a screenshot of the results, and post it here.
Welcome to the Forum!
Do You play with Keyboard and Mouse or with a controller? Did You checked all Cables of Your connected Devices and all plugged in USB Sticks?
Hey, thank you for your reply
Thanksfully, everything went better when I've moved on Xorg instead of Wayland, on the suggestion of a redditer. It doesn't bug anymore ^^
Thank you for your time and have a nice day
Because it works with the Switch, I mark Your Post as Solution.
