mkdir: cannot create directory ‘/run/user/0’: Permission denied
No protocol specified
Unable to init server: Verbindung ist gescheitert: Connection refused
Error: cannot open display: :0
Thunderbird Profiles.ini
[Profile0]
Name=Default User
IsRelative=0
Path=/run/user/1000/doc/cb8ebb73/Thunderbird.linux
Default=1
The disk where your profile is, does it show up under System Tools -> Disks?
Also, I’m guessing Thunderbird has an option where you first specified the Profile to exist on that other disk (you may have browsed to it during setup?) ? The reason I ask is because I don’t use Thunderbird (or even have it installed), so I’ll need to understand first how you initially pointed Thunderbird to your Profile when you set it up.
Can you try copying your profile to your home folder and see if Thunderbird loads with that? Just to check.
In nautilus —> Other Locations -> right click on your profile disk and select Properties. Go to Permissions-> Change Permissions for Enclosed Files. Change all to “Read and write” and “Create and delete”.