I would like to use Zorin 17, with Nvidia GTX 550 Ti, is it possible or not?

I've noticed that quite a few apps require pipewire if using Wayland which is the default compositor for Zorin by default - you can change this by selecting user name at login where a cog appears and change it to "Zorin Desktop on xorg".

Or better yet, disable Wayland altogether following my tutorial here: